2018年5月3日，江蘇師范大學(xué)鄭元林、陸軍及吳冬梅共同通訊在Molecular Medicine（IF=5.7）在線發(fā)表題為“Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia”的研究論文，該研究表明，CREB1基因沉默導(dǎo)致VD加重，這是由于抑制PKA-CREB信號通路導(dǎo)致的，從而加劇了認(rèn)知功能障礙。

但是，在2023年8月7日，該文章被撤回，主要原因是數(shù)據(jù)異常。

另外，國自然基金委對吳冬梅、鄭元林、陸軍等發(fā)表的論文共通報了35篇文章，截至2023年8月10日，已經(jīng)被撤回33篇文章（部分文章為非通報文章）。

撤銷吳冬梅國家自然科學(xué)基金項目“TRPV4介導(dǎo)軟骨藻酸處理致小鼠認(rèn)知缺陷的分子機(jī)制”（批準(zhǔn)號81400902），追回已撥資金，永久取消吳冬梅國家自然科學(xué)基金項目申請資格（自2022年1月18日起），給予吳冬梅通報批評；

決定依照《國家自然科學(xué)基金條例》第三十五條第四項，并參照《國家自然科學(xué)基金委員會監(jiān)督委員會對科學(xué)基金工作中不端行為的處理辦法（試行）》第十七條第三、四項，撤銷鄭元林國家自然科學(xué)基金項目“HDAC6激活HMGB1/RAGE信號軸介導(dǎo)Ⅱ型糖尿病小鼠認(rèn)知缺陷的機(jī)制研究”（批準(zhǔn)號81571055），追回已撥資金，取消鄭元林國家自然科學(xué)基金項目申請資格5年（2022年1月18日至2027年1月17日），給予鄭元林通報批評；

決定參照《國家自然科學(xué)基金委員會監(jiān)督委員會對科學(xué)基金工作中不端行為的處理辦法（試行）》第十七條第三、四項，取消陸軍國家自然科學(xué)基金項目申請資格5年（2022年1月18日至2027年1月17日），給予陸軍通報批評。

吳冬梅、鄭元林、陸軍合作的撤稿文章列表（截至2023年8月10日共計33篇）：

[1]Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia,Molecular Medicine；

[2]The effect of DNA-PKcs gene silencing on proliferation, migration, invasion and apoptosis, and in vivo tumorigenicity of human osteosarcoma MG-63 cells,Biomedicine & Pharmacotherapy；

[3]Long noncoding RNA nuclear enriched abundant transcript 1 impacts Cell proliferation, invasion, and migration of glioma through regulating miR-139-5p/ CDK6,Journal of Cellular Physiology；

[4]Repression of microRNA-382 inhibits glomerular mesangial cell proliferation and extracellular matrix accumulation via FoxO1 in mice with diabetic nephropathy,Cell Proliferation；

[5]Bone Marrow Mesenchymal Stem Cell-Derived Exosomal MicroRNA-126-3p Inhibits Pancreatic Cancer Development by Targeting ADAM9,Molecular Therapy: Nucleic Acids；

[6]The role of HOTAIR-induced downregulation of microRNA-126 and interleukin-13 in the development of bronchial hyperresponsiveness in neonates,Journal of Cellular Physiology；

[7]MicroRNA-152 inhibits tumor cell growth while inducing apoptosis via the transcriptional repression of cathepsin L in gastrointestinal stromal tumor. Cancer Biomarkers；

[8]PTEN gene silencing contributes to airway remodeling and induces airway smooth muscle cell proliferation in mice with allergic asthma. Journal of Thoracic Disease；

[9]MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9.Oncotarget；

[10]MicroRNA-433 inhibits oral squamous cell carcinoma cells by targeting FAK. Oncotarget；

[11]Mechanism of MicroRNA-708 Targeting BAMBI in Cell Proliferation, Migration, and Apoptosis in Mice With Melanoma via the Wnt and TGF-β Signaling Pathways. Technology in Cancer Research & Treatment；

[12]Inhibition of microRNA-200a Upregulates the Expression of Striatal Dopamine Receptor D2 to Repress Apoptosis of Striatum via the cAMP/PKA Signaling Pathway in Rats with Parkinson’s Disease. Cellular Physiology and Biochemistry；

[13]Long Non-Coding RNA LINC01260 Inhibits the Proliferation, Migration and Invasion of Spinal Cord Glioma Cells by Targeting CARD11 Via the NF-κB Signaling Pathway. Cellular Physiology and Biochemistry；

[14]Salidroside Protection Against Oxidative Stress Injury Through the Wnt/β-Catenin Signaling Pathway in Rats with Parkinson’s Disease. Cellular Physiology and Biochemistry；

[15]Micro-RNA-143 inhibits proliferation and promotes apoptosis of thymocytes by targeting CXCL13 in a myasthenia gravis mouse model. AJP Cell Physiology；

[16]MircoRNA-1275 promotes proliferation, invasion and migration of glioma cells via SERPINE1. Journal of Cellular and Molecular Medicine；

[17]S100A9 gene silencing inhibits the release of pro-inflammatory cytokines by blocking the IL-17 signalling pathway in mice with acute pancreatitis. Journal of Cellular and Molecular Medicine；

[18]Repression of microRNA-382 inhibits glomerular mesangial cell proliferation and extracellular matrix accumulation via FoxO1 in mice with diabetic nephropathy. Cell Proliferation；

[19]Protective effect of autophagy on endoplasmic reticulum stress induced apoptosis of alveolar epithelial cells in rat models of COPD. Bioscience Report；

[20]Down-regulation of XIAP enhances the radiosensitivity of esophageal cancer cells in vivo and in vitro. Bioscience Report；

[21]microRNA-136 inhibits proliferation and promotes apoptosis and radiosensitivity of cervical carcinoma through the NF-κB pathway by targeting E2F1. Life Sciences；

[22]Inhibition of the TGF-β1/Smad signaling pathway protects against cartilage injury and osteoarthritis in a rat model. Life Sciences；

[23]Effects of rehabilitation training on apoptosis of nerve cells and the recovery of neural and motor functions in rats with ischemic stroke through the PI3K/Akt and Nrf2/ARE signaling pathways. Brain Research Bulletin；

[24]Effect of microRNA-186 on oxidative stress injury of neuron by targeting interleukin 2 through the janus kinase-signal transducer and activator of transcription pathway in a rat model of Alzheimer’s disease. Journal of Cellular Biochemistry；

[25]MicroRNA-30d preserves pancreatic islet β-cell function through negative regulation of the JNK signaling pathway via SOCS3 in mice with streptozotocin-induced diabetes mellitus. Journal of Cellular Biochemistry；

[26]MicroRNA-421 suppresses the apoptosis and autophagy of hippocampal neurons in epilepsy mice model by inhibition of the TLR/MYD88 pathway. Journal of Cellular Biochemistry；

[27]Protective effects of microRNA-431 against cerebral ischemia-reperfusion injury in rats by targeting the Rho/Rho-kinase signaling pathway. Journal of Cellular Biochemistry；

[28]LncRNA LINC00880 promotes cell proliferation, migration, and invasion while inhibiting apoptosis by targeting CACNG5 through the MAPK signaling pathway in spinal cord ependymoma. Journal of Cellular Biochemistry；

[29]Down-regulated long non-coding RNA ANRIL restores the learning and memory abilities and rescues hippocampal pyramidal neurons from apoptosis in streptozotocin-induced diabetic rats via the NF-κB signaling. Journal of Cellular Biochemistry；

[30]Effects of S100A12 gene silencing on serum levels of anti-inflammatory/pro-inflammatory cytokines in septic rats through the ERK signaling pathway. Journal of Cellular Biochemistry；

[31]MicroRNA-381-induced down regulation of CXCR4 promotes the proliferation of renal tubular epithelial cells in rat models of renal ischemia reperfusion injury. Journal of Cellular Biochemistry；

[32]Effects of long noncoding RNA SPRY4-IT1-mediated EZH2 on the invasion and migration of lung adenocarcinoma. Journal of Cellular Biochemistry；

[33]MCL1 gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway. IUBMB Life.

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